Due to the fact that aquariums are as popular as other pets, they frequently become ill. The different abnormalities which are frequently problematic and have a significant impact on cultivation. There are two types of diseases that induce symptoms in aquatic animals: infectious disease and non-infectious disease. The infection is organisms that can harm aquatic animals’ health, such as viruses, bacteria, fungus, and parasites, which can cause lesions or altered situations that are visible to the animal’s owner.  Additionally to the illnesses mentioned above, due to physiological differences, aquatic creatures are cold-blooded (Poikilotherm). We frequently raise aquatic animal in a variety of containers according to our preferences, periodically changing the water, whether there is a water treatment system in place or not, what waste management system is in place. Water utilized for rearing will be obtained solely through water change. This is merely a “closed system.” Improper water quality management in this confined system frequently results in unanticipated health consequences. Non-infectious diseases account for a sizable portion of aquatic animal diseases for example: excessive ammonia in water, chlorine in tap water, too hot or excessively low temperatures, and many others, all of which contribute to a rise in the prevalence of illness. The process of determining the cause and treating disease is frequently continual. Aquatic creatures have a variety of distinct features that set them apart from warm-blooded animals. The environment frequently has an effect on many biological systems, the critical factors are aquatic immunity, pathogenic virulence, and environment.